The effect of histamine H2-receptor blockade with metiamide on serum gastrin levels in man.
نویسندگان
چکیده
Metiamide, an histamine H2-receptor antagonist which inhibits gastric acid secretion, does not lower basal serum gastrin concentration in man. Serum gastrin responses after stimulation by food were marginally higher when the stimulus of food was preceded by metiamide.
منابع مشابه
The effect of an H2-receptor antagonist on food-stimulated acid secretion, serum gastrin, and gastric emptying in patients with duodenal ulcers. Comparison with an anticholinergic drug.
The purpose of the present series of experiments was to measure and compare the effects of an anticholinergic drug (isopropamide) and an antagonist of the histamine H2 receptor (metiamide) on food-stimulated acid secretion. Patients with duodenal ulcers were stimulated by a steak meal, and acid secretion was measured by in vivo intragastric titration. The largest dose of isopropamide that can b...
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عنوان ژورنال:
- Gut
دوره 16 3 شماره
صفحات -
تاریخ انتشار 1975